Organonitrogen Compounds
eMolecules 19740-72-8 | Bicarbamic Acid Diisopropyl Ester | Toronto Research Chemicals | MFCD19443326 | 204.226 | C8H16N2O4CC(C)OC(=O)NNC(=O)OC(C)C | 250mg | 483384231
Bicarbamic Acid Diisopropyl Ester | Toronto Research Chemicals | 19740-72-8 | MFCD19443326 | 204.226 | C8H16N2O4CC(C)OC(=O)NNC(=O)OC(C)C | 250mg | 483384231
eMolecules 29553-70-6 | Medchem Express | 4-CPPC | 5mg | 789373664 | HY-123814 | 287.227 | C14H9NO6
Ambeed | 2-Amino-35-difluoropyridine | 250mg | 560592618 | A241098 | 732306-31-9 | MFCD03788760 | 130.098 | C5H4F2N2
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Medchemexpress LLC Yuanhuacine (Gnidilatidin) | 60195-70-2 | 1 MG
Yuanhuacine (Gnidilatidin), a diterpene from *Daphne genkwa*, is an effective and highly selective inhibitor of the basal-like 2 (BL2) subtype of TNBC. It can induce G2/M cell cycle arrest and exhibits broad anti-tumor activity. Yuanhuacine is an orally active DNA damaging agent.
- Highly selective inhibitor for the BL2 subtype of TNBC.
- Induces G2/M cell cycle arrest.
- Exhibits broad anti-tumor activity.
- Acts as an orally active DNA damaging agent.
- Inhibits proliferation in various cancer cell lines including H1993, H358, H460, Calu-1, H1299, A549, UMUC3, and HCT116.
- Downregulates mTOR activation.
- Inhibits migration of H1993 cells.
- Upregulates p21 transcription and protein expression by regulating Sp1 protein stability.
Medchemexpress LLC 11R-VIVIT | 592517-80-1 | 99.6% | 3573.15 | 1 MG
11R-VIVIT is a cell-permeable nuclear factor of activated T cells (NFAT) inhibitor. It can be used for the research of podocyte and diabetic nephropathy.
- Cell-permeable to inhibit NFAT activity
- Specifically targets and inhibits nuclear factor of activated T cells
- Useful for the study of podocyte and diabetic nephropathy
- Reduces NFAT2 expression in high glucose-treated podocytes in vitro
- Attenuates diabetic nephropathy symptoms and restores podocyte number in vivo
Medchemexpress LLC Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | 99.8% | 327.89 g/mol | C21H26ClN | 50 MG
Melitracen hydrochloride is the hydrochloride salt of melitracen, supplied as a high-purity research standard for analytical, pharmacological, and formulation studies. It is a white to off-white solid (CAS 10563-70-9) with defined solubility and storage recommendations to support reproducible results.
- High purity suitable for analytical and pharmacological research.
- White to off-white solid with consistent physical properties.
- Soluble in water and DMSO; may require sonication.
- Store solid at 4°C, sealed and protected from moisture; solutions at -80°C (long term) or -20°C (short term).
- Supplied in small pack sizes convenient for assay and preclinical work.
![Medchemexpress LLC 6-methyl-2-[(3-phenoxypropyl)aminomethyl]quinolin-4(1H)-one | 1434515-70-4 | 99.5% | 322.40 g·mol-1 | C20H22N2O2 | 100MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000239167.png-250.jpg)
Medchemexpress LLC 6-methyl-2-[(3-phenoxypropyl)aminomethyl]quinolin-4(1H)-one | 1434515-70-4 | 99.5% | 322.40 g·mol-1 | C20H22N2O2 | 100MG
UCSF924 is a potent and selective dopamine D4 receptor (DRD4) partial agonist used as a chemical probe in neuropsychiatric and pharmacology research. It exhibits an EC50 of 4.2 nM and a Ki of approximately 3 nM for DRD4, with reported lack of off-target activity against more than 320 non-olfactory GPCRs. Supplied as a high-purity research compound for biochemical and cellular studies. Not for human or veterinary use.
- Potent DRD4 partial agonist (EC50 4.2 nM).
- High affinity for DRD4 (Ki ≈ 3 nM).
- Demonstrated selectivity with minimal off-target GPCR activity.
- High purity suitable for biochemical and cellular assays.
- Available in multiple packaging formats and DMSO solutions for assay use.
Alkali Scientific Creatine Phosphate Disodium Salt Tetrahydrate, 1 Kg
Creatine Phosphate Disodium Salt Tetrahydrate is a high-purity compound used in energy metabolism studies. The disodium salt tetrahydrate form is highly soluble and ideal for use in biochemical assays, particularly in laboratories studying muscle metabolism and energy production. Creatine phosphate plays a crucial role in regenerating ATP, the primary energy source for cellular functions, especially in muscle cells. It is widely used in clinical chemistry, sports science, and metabolic research. This compound is typically used in laboratory preparations, clinical research, and the development of energy metabolism studies to assess creatine levels in biological systems.
eMolecules 192188-70-8 | Ambeed | 44-(14-Phenylenebis(ethyne-21-diyl))dibenzaldehyde | 100mg | 633659855 | A1226413 | 334.374 | C24H14O2
AstaTech | BIS[ALPHAALPHA-BIS(TRIFLUOROMETHYL)BENZENEMETHANOLATO]DIPHENYLSULFUR | 0.1g | 718062933 | D85638 | 95.000 | 32133-82-7 | MFCD00010662 | 672.530 | C30H20F12O2S
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Selleck Chemical LLC Clonidine HCl S2458-1g
Clonidine HCl(Kapvay) is a direct-acting 2 adrenergic agonist with an ED50 of 0 02 0 01 mg/kg
Chem-Impex International, Inc. Tetramethylfluoroformamidiniun hexafluorophosphate | 164298-23-1 | MFCD02684443 | 25G
Tetramethylfluoroformamidiniun hexafluorophosphate, 164298-23-1, MFCD02684443, 25G
eMolecules 1117-71-1 | METHYL 4-BROMOBUT-2-ENOATE | AstaTech | MFCD00000246 | 179.013 | C5H7BrO2 | 80.000 | COC(=O)\C=C\CBr | 25g | 457903317
METHYL 4-BROMOBUT-2-ENOATE | AstaTech | 1117-71-1 | MFCD00000246 | 179.013 | C5H7BrO2 | 80.000 | COC(=O)\C=C\CBr | 25g | 457903317
Medchemexpress LLC To-1187 (TFA) | 98.4% | 795.72 | 50 MG
TO-1187 TFA is a selective HDAC6 PROTAC degrader with a DC50 of 5.81 nM. It functions by promoting the ubiquitination and degradation of HDAC6. This compound is suitable for use in research studying hematological malignancies and solid tumors. The compound is composed of an HDAC6 ligand, a CRBN ligase ligand, and a linker.
- Selective HDAC6 PROTAC degrader, exhibits a DC50 of 5.81 nM, indicating potent and specific degradation of HDAC6.
- Promotes ubiquitination and subsequent degradation of HDAC6.
- Useful in the study of hematological malignancies and solid tumors.
- Consists of a specific HDAC6 ligand, a CRBN ligase ligand, and a linker.
- Purity of 98.41%.
Medchemexpress LLC PF-562271 besylate | 939791-38-5 | MFCD14105612 | 99.2% | 665.66 | C27H26F3N7O6S2 | 50 MG
PF-562271 besylate is the besylate salt of a potent, ATP-competitive, reversible inhibitor of focal adhesion kinase (FAK) and Pyk2 commonly used in preclinical biochemical and cellular research. It shows low-nanomolar activity against FAK and is supplied at high purity in small-scale packages for laboratory studies.
- Potent ATP-competitive inhibitor of FAK and Pyk2 (FAK IC50 ≈ 1.5 nM; Pyk2 IC50 ≈ 13 nM).
- Reversible mechanism suitable for biochemical assays.
- High purity for research applications (reported ~99.17%).
- Available in multiple small-scale package sizes for laboratory use.
- Suitable for cellular and signaling pathway studies.